What were your first pancreatic cancer symptoms?

When symptoms of a pancreatic tumor first appear, they most commonly include jaundice, or a yellowing of the skin and the whites of the eyes, which is caused by an excess of bilirubin—a dark, yellow-brown substance made by the liver. Sudden weight loss is also a common early warning sign of pancreatic cancer.

What is a distinctive finding in patients who have Churg-Strauss syndrome?

Most people with Churg-Strauss syndrome have a type of nerve damage that causes numbness or pain in your hands and feet. Migratory spots or lesions on a chest X-ray. These lesions typically move from one place to another or come and go. On chest X-rays, the lesions mimic pneumonia.

Is Churg-Strauss P or C Anca?

The autoantibodies antinuclear antibodies, cytoplasmic anti-neutrophil cytoplasmic antibodies (c-ANCA) and perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) were negative. These symptoms are typical for eosinophilic granulomatosis with polyangiitis (EGPA, alternatively known as Churg-Strauss syndrome).

How common is Churg-Strauss syndrome?

EGPA seems to affect men and women equally. Around 11-13 people per million are diagnosed with EGPA. The average age of someone with a new diagnosis is 40 years old, and it is very rare in children or those over 65 to be diagnosed.

What do you need to know about Churg Strauss syndrome?

Churg-Strauss syndrome. Overview. Churg-Strauss syndrome is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to organs and tissues, sometimes permanently damaging them. This condition is also known as eosinophilic granulomatosis with polyangiitis (EGPA).

What happens in the vasculitic stage of Churg Strauss?

Vasculitic stage. The hallmark of this stage of Churg-Strauss syndrome is severe blood vessel inflammation (vasculitis). By narrowing blood vessels, inflammation reduces blood flow to vital organs and tissues throughout your body, including your skin, heart, peripheral nervous system, muscles, bones and digestive tract.

How does IVIG therapy work for Churg Strauss syndrome?

According to some reports, in some individuals with Churg-Strauss syndrome, monthly IVIG therapy may result in decreased levels of certain white blood cells (eosinophils), improved lung (pulmonary) function, and additional improvement of other associated symptoms and findings.

When was zafirlukast approved for Churg Strauss syndrome?

In some cases, Churg-Strauss syndrome has been associated with use of zafirlukast (Accolate), a nonsteroidal medication that was approved in 1996 as a therapy for the prevention and treatment of asthma in individuals 12 years of age and older.