How much does Syprine cost in Canada?

As of January 1, 2014, Valeant Pharmaceuticals, the North American manufacturer of trientine (trade name ‘Syprine’), terminated its program whereby Syprine was made available to Canadian patients with Wilson disease at no cost and simultaneously changed its price from approximately $800 per 100 tablets to approximately …

What is the cost of Syprine?

The cost for Syprine oral capsule 250 mg is around $22,212 for a supply of 100 capsules, depending on the pharmacy you visit….Oral Capsule.

Quantity Per unit Price
100 $222.12 $22,212.04

Is there a generic for Syprine?

Dr. Reddy’s is offering trientine hydrochloride capsules in a dosage strength of 250 mg. The product is the generic of Alton Pharma’s Syprine (trientine hydrochloride) capsules.

Who manufactures Syprine?

Syprine, which treats a rare condition known as Wilson disease, gained notoriety after Valeant Pharmaceuticals International raised the price of the drug to $21,267 in 2015 from $652 just five years earlier.

What is Clovique?

Clovique (trientine hydrochloride capsules) is a chelating compound used to treat patients with Wilson’s disease who are intolerant of penicillamine.

How much does it cost to treat Wilson’s disease?

The current price for Syprine is ∼$200 per 250-mg capsule and Cuprimine costs ∼$55-$60 per 250-mg tablet. 1 The annual cost for the average daily adult dose of Syprine (1,000 mg) is ∼$300,000, making it the most costly treatment for any liver disease to date.

When should I take penicillamine?

It is usually taken on an empty stomach at least 1 hour before or 2 hours after a meal, and at least 1 hour before or after any food or milk. For the treatment of Wilson’s disease and cystinuria, penicillamine is usually taken four times a day.

Is Wilson’s disease fatal?

Untreated, Wilson’s disease can be fatal. Serious complications include: Scarring of the liver (cirrhosis). As liver cells try to make repairs to damage done by excess copper, scar tissue forms in the liver, making it more difficult for the liver to function.

Why is Zolgensma so costly?

The reason for its exorbitant cost is its miniscule market size in the drug manufacturing industry and its potential to save lives. “The disorder is rare and that is why we needed a highly specialized drug. The expertise required to make it and the research around it has taken very long.

What was the price of Syprine in 2015?

Syprine, which treats a rare condition known as Wilson disease, gained notoriety after Valeant Pharmaceuticals International raised the price of the drug to $21,267 in 2015 from $652 just five years earlier.

How much did Valeant raise the price of Syprine?

Valeant gained notoriety after raising the price of the drug Syprine from $652 to more than $21,000. A spokeswoman for Teva declined to comment on how it set its price, but said the company considers a range of factors.

Is it possible to get a generic Syprine?

But as the Syprine case shows, it often isn’t as simple as adding a single generic competitor. “By and large, generics work when there are multiple players,” said David Maris, an analyst at Wells Fargo who wrote this week about Teva’s generic Syprine price. “When there’s not, you get this.”

Is there a copycat version of Syprine?

When Teva Pharmaceuticals announced recently that it would begin selling a copycat version of Syprine — an expensive drug invented in the 1960s — the news seemed like a welcome development for people taking old drugs that have skyrocketed in price.