What is IARC classification?

The International Agency for Research on Cancer (IARC) have devised a system of categories to evaluate the carcinogenicity of an agent to humans. An agent is classified based on scientific evidence derived from human and experimental animal studies and from mechanistic and other relevant data.

What are the 4 types of carcinogens?

Pollution & Exposure to Chemicals A few well-known carcinogens are asbestos, nickel, cadmium, radon, vinyl chloride, benzidene, and benzene. These carcinogens may act alone or with another carcinogen to increase your risk. For example, asbestos workers who also smoke have a higher risk of lung cancer.

What is the full form of IARC?

IARC – INTERNATIONAL AGENCY FOR RESEARCH ON CANCER.

What is carcinogenicity explain with 2 examples?

Carcinogens are substances or factors that can cause cancer. Examples can include chemicals, medical or environmental radiation, some viruses, lifestyle factors, and even some medications.

Is Coca Cola a carcinogen?

New chemical analyses have found that Coca-Cola, Pepsi-Cola, Diet Coke, and Diet Pepsi contain high levels of 4-methylimidazole (4-MI), a known animal carcinogen.

What is the use of 2-acetylaminofluorene in humans?

2-Acetylaminofluorene is used by scientists to study the carcinogenicity and mutagenicity of aromatic amines. No information is available on the acute (short-term), chronic (long-term), reproductive, or developmental effects of 2-acetylaminofluorene in humans. It has caused a variety of tumors in laboratory animals.

What are the classifications in the IARC monographs?

The list of agents classified by the IARC Monographs has been updated. It now includes all evaluations up to volume 101.

What happens to 2-acetylaminofluorene when heated to decomposition?

When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) 2-acetylaminofluorene appears as white powder or light beige solid. (NTP, 1992)