What is gamma hydroxybutyric acid used for?
GHB is a depressant that acts on the central nervous system. It is purported as a strength enhancer, euphoriant and aphrodisiac and is one of several agents reported as being used as a “date rape” drug.
Is GHB an amino acid?
The biosynthesis and metabolism of GHB is also closely linked to GABA metabolism and GHB can be considered both a metabolite and a precursor of GABA. The amino acid glutamate passes the blood-brain barrier and is decarboxylated to produce GABA.
What was GHB developed for?
narcolepsy
Efforts to ban GHB caused increased use of GHB analogues and pro-drugs. Against this backdrop, GHB was being developed for the treatment of narcolepsy, leading to the approval of Xyrem (sodium oxybate) oral solution in 2002 for the treatment of cataplexy in patients with narcolepsy.
Where is gamma hydroxybutyrate found?
Gamma hydroxybutyrate (GHB) is a chemical found in the brain and other areas of the body. It can also be made in a laboratory. GHB used to be available as a dietary supplement in the U.S., but it was taken off the market in 1990 because of safety concerns.
How is gamma hydroxybutyrate ingested?
GHB is mainly self-ingested orally in a liquid mixture. It is sometimes mixed with alcohol to intensify its effects resulting in respiratory depression and coma. The average oral dose ranges from 1 to 5 grams (depending on the purity of the compound this can be 1-2 teaspoons mixed in a beverage).
How much GHB do I need to sleep?
For narcolepsy and its symptoms: A dose of 25 mg/kg at bedtime, repeated 3 hours later. GHB should be used only under close medical supervision.
Is beta hydroxybutyrate bad for you?
When taken by mouth: BHB is POSSIBLY SAFE when taken as a single dose once. Some people might have stomach upset, diarrhea, constipation, and stomach pain. These side effects are more likely to happen when very high doses are used. When applied into the eye: BHB is POSSIBLY SAFE.
What is the street name for GHB drug?
(Street Names: GHB, G, Gina, Liquid Ecstasy, Liquid X, Liquid G, Goop, Georgia. Home Boy, Grievous Bodily Harm, Easy Lay)
Does GHB improve sleep?
GHB administered before nocturnal or diurnal sleep increases stages 3 and 4 and decreases stage 1 non-rapid eye movement (NREM) sleep. In addition, GHB improves REM efficiency at night and reduces wake time after sleep onset when administered before a morning nap recording.
Do people still use GHB?
GHB was made illegal in the US by the Food and Drug Administration (FDA) in 1990 for these reasons. However, in 2002, it was approved for the treatment of a common symptom of narcolepsy, though it is still highly controlled and recreational use remains illegal.
Does keto hurt your kidneys?
Keto Can Put Stress on the Kidneys and Possibly Give You Kidney Stones. Kidney stones are a well-noted potential side effect of the ketogenic diet.
Who should not take keto BHB?
As recommended by the manufacturers, pregnant women and women who are breastfeeding shouldnt use the supplements. The pills can also be harmful to kids below 18 years of age. How often can one take the Keto BHB capsules?