What is the histology of the spleen?

The spleen is comprised of red pulp and white pulp. The red pulp is the site of blood filtration and the white pulp is lymphoid tissue that responds to blood-borne antigens. There is a dense connective tissue capsule that sends conspicuous trabeculae to partially subdivide the organ.

What is the splenic capsule made of?

The spleen is surrounded by a capsule composed of dense fibrous tissue, elastic fibers, and smooth muscle. The outermost layer of the splenic capsule is composed of mesothelial cells, which may not be evident on histologic section.

What is white and red pulp?

White pulp is material which is part of the immune system (lymphatic tissue) mainly made up of white blood cells. Red pulp is made up of blood-filled cavities (venous sinuses) and splenic cords.

What is the structure and function of the spleen?

The spleen sits in the upper left of the abdomen, protected by the rib cage. It is the largest organ of the lymphatic system — the circulation of the immune system. It recycles old red blood cells and stores platelets (components of the blood that help stop bleeding) and white blood cells.

What is trabeculae of spleen?

The spleen is covered by a dense capsule, and there are connective tissue trabeculae, which provide internal support for the spleen, and carry the blood vessels into the spleen. It shows how the artery has a lymphoid sheath surrounding the artery, as it enters the spleen, with aggregations of secondary lymphoid tissue.

What kind of epithelium is in the spleen?

Discontinuous endothelium allows blood cells and larger proteins to pass through the vessels. This type of endothelium is present in the sinusoids of the liver, spleen, and bone marrow.

How does blood enter the spleen?

Blood enters the spleen through the splenic artery, moves through the sinuses where it is filtered, then leaves through the splenic vein. The spleen filters blood in much the way that the lymph nodes filter lymph.

What is the function of red and white pulp in the spleen?

Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells. The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp….

Red pulp
Latin pulpa splenica

What is the function of spleen in immune system?

Your spleen’s main function is to act as a filter for your blood. It recognizes and removes old, malformed, or damaged red blood cells. When blood flows into your spleen, your spleen performs “quality control”; your red blood cells must pass through a maze of narrow passages.

What is the function of Trabeculae in the spleen?

The spleen is covered by a dense capsule, and there are connective tissue trabeculae, which provide internal support for the spleen, and carry the blood vessels into the spleen.

What is the job of the spleen?

One of the spleen’s main jobs is to filter your blood. It affects the number of red blood cells that carry oxygen throughout your body, and the number of platelets, which are cells that help your blood to clot. It does this by breaking down and removing cells that are abnormal, old, or damaged.

What is the spleen responsible for?

The spleen dominates the muscles and four limbs. Since the spleen is responsible for transforming food into qi and blood and transporting them throughout the body, proper functioning of the organ is essential to maintain muscle mass and strong limbs.

What is the spleens function?

The spleen is an organ about the size of a clenched fist found on the left-hand side of your upper tummy (abdomen). Its main functions are to filter your blood, create new blood cells and store platelets.

What system is the spleen part of?

The spleen is part of your body’s lymphatic system. The lymphatic system helps remove cellular waste, maintain fluid balance, and make and activate infection-fighting white blood cells for the immune system.