What is ASME BPE standard?

ASME BPE (American Society of Mechanical Engineers: Bioprocessing Equipment) is an international standard developed as an aid for the design and construction of equipment intended for use in the manufacturing of biopharmaceuticals. New editions of the standard are generally approved and published every two years.

What is BPE certification?

ASME Bioprocessing Equipment (BPE) Certification is a company level certification for organizations manufacturing or supplying tubing and fittings under the scope of the ASME standard “Bioprocessing Equipment”, which dictates specific conditions for design, materials, construction, surface finish and inspection.

How do you calculate CIP flow rate?

And, to determine the required flow and pressure needed to clean a vessel with a static spray ball, you multiply the circumference of the vessel in feet by three gallons per minute (gpm) per foot of circumference to create a flow turbulence to clean the vessel’s interior.

How do you size a CIP system?

CIP system sizing is determined by dimensions of the vessels and pipelines to be cleaned. Supply pump flow is determined by the vessel size and the largest pipeline diameter. Turbulent cleaning action requires 5-7 fps flow in lines. Proper cascading cleaning action by a sprayball is 3 gpm per ft of tank circumference.

What does BPE stand for in piping?

The short answer is that BPE stands for bioprocessing equipment. The longer answer is that it’s the body of standards for bioprocessing equipment developed by the American Society of Mechanical Engineers (ASME), composed of volunteer professionals worldwide in 36 technical sub-fields.

What are BPE fittings?

BPE Weld Fittings Bioprocessing equipment (BPE) fittings are a special type of fitting used for high-purity end markets, such as biotech, pharmaceutical, cosmetic , personal care, and semiconductor that require strict cleanliness and production practices.

What does BPE 4 indicate?

– Code 4: if there is a code 4 in any sextant, then record full probing depths (6 sites per. tooth) throughout the entire dentition. • BPE cannot be used to assess the response to periodontal therapy because it does not. provide information about how sites within a sextant change after treatment.

What does BPE stand for?

Bachelor of Physical Education
abbreviation. Bachelor of Physical Education.

What is CIP process?

Clean-in-place (CIP) is a method of automated cleaning the interior surfaces of pipes, vessels, equipments, filters and associated fittings, without major disassembly. CIP is commonly used for equipment such as piping, tanks, and fillers. CIP employs turbulent flow through piping, or sprayballs for large surfaces.

What CIP means?


Acronym Definition
CIP Carriage and Insurance Paid to (shipping)
CIP Congenital Insensitivity to Pain (rare condition)
CIP Continuation In Part
CIP Case In Point

How many types of CIP are there?

Depending on the situation and scale, there are two types of CIP cleaning systems. They are single use and re-use systems. Use and throw of the cleaning solutions as single use system is not much in use. Now there are combined systems using advantages of both single use and reuse systems also.

What is the full form of BPE?

From Wikipedia, the free encyclopedia. A Bachelor of Physical Education (BPE or BPhEd) is a bachelor degree granted by some universities.

When did the ASME BPE standard come out?

The BPE Standard, first issued in 1997, dovetails nicely with the ASME B31.3 Process Piping Code, the essential piping Code for industry in general. The initial BPE Standard consisted of six Parts, which included:

What are the ASME BPE guidelines for CIP?

Incorporating The ASME BPE Guidelines For CIP For Biopharma Equipmen… CIP guidelines for Processing Skids and Transfer Lines for Bio Pharmaceutical Industry. 1.

What are the requirements for Bioprocessing Equipment ASME?

The initial subcommittees were (1) General Requirements (2) Design Relating to Sterility and Cleanability of Equipment (3) Dimensions and Tolerances (4) Material Joining (5) Surface Finishes (6) Seals (c) Throughout the development of the Standard, close liaison was made with the European CEN, ASTM, and the 3-A Dairy Standards.

What is the flow rate of the asmebpe?

FLow rAtE • The ASME®BPE standard targets a flow rate of 2.5 to 3 gpm (9.4 to 11.4 lpm) per foot (0.3 m) of inner vessel circumference using a 180° up spray ball. This flow results in a turbulent sheeting action down the vessel walls.