What is chromosome 46,XY?
A 46, XY disorder of sex development (DSD) is a condition in which an individual with one X chromosome and one Y chromosome in each cell , the pattern normally found in males, have genitalia that is not clearly male or female.
What is karyotype 46xx?
A 46,XX karyotype in a newborn with ambiguous genitalia indicates that the child is a genetic female who was exposed to excessive amounts of androgens during fetal life.
Can someone with XY chromosomes get pregnant?
Males and most XY females cannot become pregnant because they don’t have a uterus. The uterus is where the fetus develops, and pregnancy isn’t possible without it. In most cases, having a Y chromosome means having no uterus, so pregnancy isn’t possible.
How do you know if you have Swyer syndrome?
A diagnosis of Swyer syndrome is usually made when young adults are tested for delayed puberty. Molecular genetic testing can determine whether one of the specific gene mutations that are associated with Swyer syndrome is present in an affected individual.
Is there such a thing as 46, XX, XY?
46,XX/46,XY is an exceptionally rare chimeric genetic condition characterized by the presence of some cells that express a 46,XX karyotype and some cells that express a 46,XY karyotype in a single human being.
What is a 46, XY disorder of sex development?
A 46, XY disorder of sex development (DSD) is a condition in which an individual with one X chromosome and one Y chromosome in each cell, the pattern normally found in males, have genitalia that is not clearly male or female.
What does the karyotype 46, XY stand for?
A 46,XY karyotype reveals that one is dealing with a genetic male who was undermasculinized during fetal development. Laboratory findings of normal or elevated testosterone and DHT indicate a diagnosis of AIS.
What happens to the Y chromosome in 45, x / 46, XY?
In 45,X/46,XY, most or all of the Y chromosome is lost in one of the newly created cells. All the cells then made from this cell will lack the Y chromosome.