What is conjunctival papilloma?

Conjunctival papilloma is an acquired benign epithelial tumor of the conjunctiva and may manifest as sessile or pedunculated conjunctival mass. A close causal relationship between human papillomavirus (HPV) and conjunctival papilloma has been reported. [1] Conjunctival papilloma often requires surgical excision.

How common is conjunctival papilloma?

HPV types 16 and 18 commonly are associated with not only high-grade cervical intraepithelial neoplasia and invasive carcinoma but also squamous cell dysplasia and carcinoma of the conjunctiva. The recurrence rate for infectious papillomas is high. Limbal papillomas have a recurrent rate of 40%.

Can eye papilloma turn into cancer?

The eyelid papilloma is one of the most common eyelid tumors and usually occurs in middle-aged or elderly patients. It is benign, painless, and carries little to no risk for growth into cancer.

How do you describe papilloma?

Medical Definition of papilloma : a benign tumor (as a wart or condyloma) resulting from an overgrowth of epithelial tissue on papillae of vascularized connective tissue (as of the skin) — see papillomavirus.

Can I get HPV in my eye?

Human papillomavirus infection is considered the most common sexually transmitted disease and can infect the ocular surface, as well (1-3). The mode of transmission of HPV infection to the conjunctiva in adults is considered autoinoculation from contaminated fingers in the majority of cases.

How is eyelid papilloma treated?

The standard of treatment for most eyelid papillomas is surgical excision. Due to the proximity to the eye, especially if the lesion is near the margin, cutting it away is safer than most alternative procedures.

How do you treat papillomas?


  1. cautery, which involves burning off the tissue and then scraping it away using curettage.
  2. excision, in which a doctor surgically removes the papilloma.
  3. laser surgery, a procedure that destroys the wart using high-energy light from a laser.
  4. cryotherapy, or freezing off the tissue.

Are papillomas common?

It’s most common in women over 40 and usually develops naturally as the breast ages and changes. Men can also get intraductal papillomas but this is very rare. Intraductal papilloma is not the same as papillary breast cancer although some people confuse the two conditions because of their similar names.

Is there such a thing as a conjunctival papilloma?

[…] Conjunctival papilloma is an acquired benign squamous cell tumor that can present at any age, but most frequently in the third and fourth decades of life. Papillomas have been associated with human papilloma virus (HPV) infection, usually types 6 and 11.

What is the recurrence rate of conjunctival papillomas?

The recurrence rate for infectious papillomas is high. Limbal papillomas have a recurrent rate of 40%. Conjunctival papillomas (squamous cell, limbal, or inverted) are not life threatening. Conjunctival papillomas may be large enough to be displeasing or cosmetically disfiguring.

What kind of imaging is used to diagnose conjunctival papilloma?

Although histopathological diagnosis remains the gold standard, the advent of newer non-invasive imaging modalities such as optical coherence tomography (OCT) is transforming the way we diagnose and treat ocular surface tumors, including conjunctival papilloma.

Why is an inverted conjunctival papilloma called a mucoepidermoid?

Because of its gross appearance, limbal papillomas are typed as sessile. Although rare, inverted conjunctival papillomas sometimes are referred to as mucoepidermoid papillomas because these lesions possess both a mucous component and an epidermoid component.