Why organ-on-a-chip is good?
Speeding up research First, the main advantage of these chips is that they can be manufactured for a very low cost and this can allow to test the effect of a wide range of drug concentration on the efficiency of the medicine. This will allow organs on chip technology to considerably accelerate scientific research.
What is organ-on-a-chip technology?
The organ-chips are designed to accurately recreate the natural physiology and mechanical forces that cells experience in the human body. The chips are lined with living human cells and their tiny fluidic channels reproduce blood and/or air flow just as in the human body.
Why do organs have chips?
The application of microfluidics in organs-on-chips enables the efficient transport and distribution of nutrients and other soluble cues throughout the viable 3D tissue constructs.
What are the 2 most important organs in a human?
While your heart is a vital organ, the brain (and the nervous system that attaches to the brain) make up the most critical organ system in the human body.
What is lab on a chip used for?
A lab-on-a-chip is a miniaturized device that integrates into a single chip one or several analyses, which are usually done in a laboratory; analyses such as DNA sequencing or biochemical detection.
What kind of chip is an organ on a chip?
An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ.
Are there organs on chips for animal testing?
These microdevices, called ‘Organs-on-Chips’ (Organ Chips), offer a potential alternative to traditional animal testing.
How is microfluidics used in organs on chips?
The application of microfluidics in organs-on-chips enables the efficient transport and distribution of nutrients and other soluble cues throughout the viable 3D tissue constructs.
How are Organ chips used in drug testing?
Organ Chips are now being explored worldwide as tools for accurately predicting drug efficacies and toxicities, with the goal of dramatically improving the accuracy and efficiency of preclinical drug testing. 7/7 Patent drawing of original Lung-on-a-Chip design.