What are lipoproteins and their function slideshare?
LIPOPROTEINS Definition: A lipoprotein is a biochemical assembly that contains both proteins and lipids , bound to the proteins , which allow fats to move through the water inside and outside cells.
What is lipoproteins and their functions?
Function. Lipoproteins provide a transport for lipids as described below. Transport of cholesterol to organs and tissues; cholesterol is required for the formation of membranes of red blood cells and for the production of steroid hormones. In the liver it is converted to bile acids.
What is the structure of a lipoprotein?
Lipoproteins are complex particles that have a central hydrophobic core of non-polar lipids, primarily cholesterol esters and triglycerides. This hydrophobic core is surrounded by a hydrophilic membrane consisting of phospholipids, free cholesterol, and apolipoproteins (Figure 1).
What are lipoproteins write their composition and general Structure?
Lipoproteins are special particles made up of droplets of fats surrounded by a single layer of phospholipid molecules. Phospholipids are molecules of fats which are attached to a phosphorus-containing group. They are distinctive in being amphipathic, which means they have both polar and non-polar ends.
What is lipoprotein and its classification?
Lipoproteins are classified based on their density, electrophoretic mobility, and nature of apoprotein content. Upon centrifugation, lipoproteins with high protein content sediment easily due to their high density whereas lipoproteins with high lipid content have low density and will float on the surface.
What are the two main types of lipoproteins?
Two types of lipoproteins carry cholesterol to and from cells. One is low-density lipoprotein, or LDL. The other is high-density lipoprotein, or HDL.
What are the two types of lipoproteins?
LDL and HDL Cholesterol: “Bad” and “Good” Cholesterol. Cholesterol travels through the blood on proteins called “lipoproteins.” Two types of lipoproteins carry cholesterol throughout the body: LDL (low-density lipoprotein), sometimes called “bad” cholesterol, makes up most of your body’s cholesterol.
What are examples of lipoproteins?
Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins. Examples include plasma lipoprotein particles (HDL, LDL, IDL, VLDL and chylomicrons). Subgroups of these plasma particles are primary drivers or modulators of atherosclerosis.
What is Apoprotein function?
Apolipoproteins are amphipathic molecules capable of interacting with both the lipids of the lipoprotein core and the aqueous environment of the plasma. They function as biochemical keys, allowing lipoprotein particles access to specific sites for the delivery, acceptance, or modification of lipids.
What is the function of Apolipoproteins?
Specific apolipoproteins function in the regulation of lipoprotein metabolism through their involvement in the transport and redistribution of lipids among various cells and tissues, through their role as cofactors for enzymes of lipid metabolism, or through their maintenance of the structure of the lipoprotein …
How are lipoproteins used in the biochemical assembly?
LIPOPROTEINS Definition: A lipoprotein is a biochemical assembly that contains both proteins and lipids , bound to the proteins , which allow fats to move through the water inside and outside cells. 2. The proteins serve to emulsify the lipid molecules. Many enzymes, transporters, structural proteins, antigens, and toxins are lipoproteins.
Which is a part of the lipoprotein complex?
Introduction • Lipoproteins are molecular complexes that consist of lipids & proteins (conjugated proteins). • Protein part is called apolipoprotein. • Usually abbreviated as Lp. • They function as transport vehicles for lipids in blood plasma.
What is the objective of the lipoprotein LPs?
4. Its objective is to solubilize lipids in plasma to facilitate their transport in biological system & provide efficient mechanism for lipid delivery to the tissues and lipid removal from the tissues. LPs possess the fundamental properties of micelle except the fact that, micelle is composed of amphipathic (polar) lipids only.
How are apolipoproteins different from other lipo proteins?
General Structure of Lipo proteins Some apolipoproteins are integral and cannot be removed, whereas others can be freely transferred to other lipoproteins. 12/22/13 Biochemistry for medics 4 5. Classification of Lipoproteins Lipoproteins can be classified in three ways1) Based on density- They are separated by Ultracentrifugation.