What is delavirdine used for?
Delavirdine is used along with other medications to treat human immunodeficiency virus (HIV) infection. Delavirdine is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood.
What is the mechanism of action of delavirdine?
Delavirdine is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of delavirdine is as a Non-Nucleoside Reverse Transcriptase Inhibitor.
Is delavirdine a Nnrti?
The four FDA-approved NNRTIs are nevirapine, delavirdine, efavirenz, and etravirine, and several compounds are in clinical development.
What is nucleoside reverse transcriptase inhibitors used for?
HIV/AIDS Glossary Nucleoside reverse transcriptase inhibitors (NRTIs) block reverse transcriptase (an HIV enzyme). HIV uses reverse transcriptase to convert its RNA into DNA (reverse transcription). Blocking reverse transcriptase and reverse transcription prevents HIV from replicating.
Which drug is reverse transcriptase inhibitors?
Reverse Transcriptase Inhibitors
| Drug | Drug Description |
|---|---|
| Lamivudine | A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. |
| Adefovir dipivoxil | A nucleotide analog used to treat chronic hepatitis B. |
| Emtricitabine | A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. |
What does Nnrti stand for?
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) bind to and block HIV reverse transcriptase (an HIV enzyme). HIV uses reverse transcriptase to convert its RNA into DNA (reverse transcription).
What is a non-nucleoside drug?
What are NNRTIs? Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are antiviral agents that bind non-competitively to HIV-1’s reverse transcriptase and prevents viral RNA conversion to DNA. They are used to treat human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).
What drug class is 3TC?
3TC belongs to a group of drugs called nucleoside analogues. 3TC interferes with an enzyme called reverse transcriptase (RT), which is used by HIV-infected cells to make new viruses. Since 3TC inhibits, or reduces, the activity of this enzyme, this drug causes HIV-infected cells to produce less HIV.
Delavirdine is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of delavirdine is as a Non-Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of delavirdine is Non-Nucleoside Analog.
How does delavirdine work against HIV type 1?
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Delavirdine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme’s catalytic site.
What kind of acid salt is delavirdine mesylate?
Delavirdine mesylate is the monomethanesulfonic acid salt of delavirdine, a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals…
Who is the manufacturer of delavirdine reverse transcriptase inhibitor?
Delavirdine (DLV) (brand name Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare.