What is Lrinec score?

Conclusions: The LRINEC score is a robust score capable of detecting even clinically early cases of necrotizing fasciitis. The variables used are routinely measured to assess severe soft tissue infections. Patients with a LRINEC score of > or = 6 should be carefully evaluated for the presence of necrotizing fasciitis.

What does Lrinec stand for?

laboratory risk indicator for necrotizing fasciitis
The LRINEC (laboratory risk indicator for necrotizing fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.

What is Fournier gangrene?

Fournier gangrene is an acute necrotic infection of the scrotum; penis; or perineum. It is characterized by scrotum pain and redness with rapid progression to gangrene and sloughing of tissue.

Why is clindamycin used for necrotizing fasciitis?

Necrotizing fasciitis: Subtherapeutic amounts of clindamycin may have activity against toxin production by S aureus and toxin-producing streptococci. In in vitro and animal models, clindamycin decreases toxin production in necrotizing fasciitis caused by invasive group A streptococci.

How fast does necrotizing fasciitis show symptoms?

The early symptoms of an infection with flesh-eating bacteria usually appear within the first 24 hours of infection. Symptoms are similar to other conditions like the flu or a less serious skin infection.

What does the LRINEC score mean for NF?

The LRINEC score was mainly developed as a mean to distinguish NF from other non-necrotizing soft tissue infections based on clinical determinations that are common for most diagnoses of soft tissue conditions.

Is there a scoring system for Fournier’s gangrene?

A simplified prognostic scoring system for Fournier’s gangrene. Urol Nephrol Open Access J. 2014;1(3):79‒82. scoring system with a maximum score of eighteen points denoting the highest risk of mortality and a minimum score of eight points carrying a relatively lower risk of mortality.

When to use LRINEC score in external validation?

Note: Use with caution, as the LRINEC Score has performed poorly in external validation, most recently in Neeki 2017. Patient with a concerning history or physical exam (pain out of proportion to exam, rapidly progressive cellulitis, for example). Patient with an unconcerning story (can provide some reassurance if score is very low).

When to use LRINEC score for soft tissue infection?

The score may be helpful in providing an overall gestalt picture of a patient with a potential necrotizing soft tissue infection — but it cannot rule out this infection. All patients with a high clinical suspicion for necrotizing fasciitis should receive immediate surgical consultation for potential operative debridement.